Wenyun Gao
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一种1-脱氧-D-木酮糖5-磷酸还原异构化酶抑制剂
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Affilication of Author(s):生命科学学院

Patent Coverage:国内

School Sign:第一单位

Note:本发明提出一种新类型的1-脱氧-D-木酮糖5-磷酸还原异构化酶(IspC)抑制剂,主要有:茶黄素(TF)、茶黄素3,3’-双没食子酸酯(TF3,3’G)、茶黄素-3-没食子酸酯(TF3G)、茶黄素-3’-没食子酸酯(TF3’G)、没食子儿茶素没食子酸酯(GCG)、表没食子儿茶素没食子酸酯(EGCG)、没食子酸(G)、没食子儿茶素(GC)、表没食子儿茶素(EGC)、及表儿茶素没食子酸酯(ECG)等,其中TF3,3’G、TF3G、TF3’G、GCG抑制活性非常显著;在上述部分化合物的苯丙酸及其类似物的衍生物中,茶黄素(TF)的咖啡酸衍生物对IspC的抑制活性也非常显著。

Type of Patent:发明专利

State of Patent:有效

Application Number:CN201510641068.2

Authorization number:ZL201510641068.2

Service Invention or Not:yes

Application Date:2015-09-30

Publication Date:2016-01-27

Authorization Date:2019-03-25

First Author:高文运

Personal information

Professor
Supervisor of Master's Candidates

Name (English):Wenyun Gao

Name (Pinyin):gaowenyun

Date of Birth:1967-02-12

Date of Employment:2006-07-01

School/Department:生命科学学院

Education Level:With Certificate of Graduation for Doctorate Study

Gender:Male

Degree:博士

Status:Employed

Alma Mater:中国科学院上海药物有机所

Discipline:Pharmaceutical Chemistry

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