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核酸生物学
结构生物学
微生物侵染与免疫系统响应
计算生物学与理性药物设计
- Structural insights into target DNA recognition and cleavage by the CRISPR-Cas12c1 system. Nucleic Acids Research 2022, 50, 11820-11833.
- Mechanistic insights into the R-loop formation and cleavage in CRISPR-Cas12i1. Nature Communications 2021, 12, 1-13.
- Functional features and current applications of the RNA-targeting type VI CRISPR-Cas systems. Advanced Science 2021, 2004685, 1-23.
- Two HEPN domains dictate CRISPR RNA maturation and target cleavage in Cas13d. Nature Communications 2019, 10, 1-11.
- Structural insights into Cas13b-guided CRISPR RNA maturation and recognition. Cell Research 2018, 28, 1198-1201.
- Human 3-alplha hydroxysteroid dehydrogenase type 3: structural clues of 5α-DHT reverse binding and enzyme down-regulation decreasing MCF7 cell growth. Biochemical Journal 2016, 473, 1037-1046.
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