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个人信息：Personal Information
教师拼音名称：zhangbo
电子邮箱：
入职时间：2023-02-24
所在单位：医学院
职务：教授
办公地点：医学楼-北楼316室
学位：博士学位
毕业院校：拉瓦尔大学医学院（加拿大）
学科：生物化学与分子生物学
细胞生物学
生物物理学
- Structural insights into target DNA recognition and cleavage by the CRISPR-Cas12c1 system.Nucleic Acids Research,2022,50(20):11820-11833
- Mechanistic insights into the R-loop formation and cleavage in CRISPR-Cas12i1.Nature Communications,2021,12(3476):1-13
- Functional features and current applications of the RNA-targeting type VI CRISPR-Cas systems.Advanced Science,2021,2004685(1-23
- Two HEPN domains dictate CRISPR RNA maturation and target cleavage in Cas13d.Nature Communications,2019,10(2544):1-11
- Structural insights into Cas13b-guided CRISPR RNA maturation and recognition.Cell Research,2018,28(12):1198-1201
- Human 3-alplha hydroxysteroid dehydrogenase type 3: structural clues of 5α-DHT reverse binding and enzyme down-regulation decreasing MCF7 cell growth.Biochemical Journal,2016,473(8):1037-1046
- Human 3-alpha hydroxysteroid dehydrogenase type 3 (3α-HSD3): the V54L mutation restricting the steroid alternative binding and enhancing the 20α-HSD activity.Journal of Steroid Biochemistry and Molecular Biology,2014,141(135-143
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