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高精度糖蛋白质组学，包括：建立基于生物质谱分析的高精度糖蛋白质组学新方法、开发高通量自动化糖链结构解析的新软件、并用于重大疾病特别是恶性肿瘤生物标志物和治疗靶点发现研究。
- 71. Jun Li#, Didi Liu#, Yingjie Zhang, Jiechen Shen, Wei Dan, Zexuan Chen, Shisheng Sun*. Site-specific analysis of core and antenna fucosylation on serum glycoproteins. Analytical Chemistry. 2024, DOI: 10.1021/acs.analchem.4c00445. 2024,
- 70. Jiechen Shen, Bojing Zhu, Zexuan Chen, Li Jia, and Shisheng Sun*. Precision Characterization of Site-Specific O-Acetylated Sialic Acids on N-Glycoproteins. Analytical Chemistry. 2023, 95 (3): 1995–2003.
- 69. Pengfei Li, Zexuan Chen, Shanshan You, Yintai Xu, Zhifang Hao, Didi Liu, Jiechen Shen, Bojing Zhu, Wei Dan, Shisheng Sun*. Application of StrucGP in medical immunology: site-specific N‑glycoproteomic analysis of macrophages. Frontiers of Medicine. 2023, 17(2): 304-316
- 68. Wenbo Dong, Lin Chen, Li Jia, Zexuan Chen, Jiechen Shen, Pengfei Li, Shisheng Sun*. Maximal performance of intact N-glycopeptide enrichment using sequential HILIC and MAX columns. Analytical and Bioanalytical Chemistry. 2023, 415: 6431–6439.
- 67. Liuyi Dang#, Pengfei Li#, Wei Dan, Huanhuan Liu, Jiechen Shen, Bojing Zhu, Li Jia, Shisheng Sun*. Glycoproteomic analysis of regulatory effects of bisecting N-glycans on N-glycan biosynthesis and protein expressions in human HK-2 cells. Carbohydrate Research. 2023, 531: 108894.
- 66. Cheng Li#, Wei Dan#, Pengfei Li, Miaomiao Xin, Rongxia Lan, Bojing Zhu, Zexuan Chen, Wenbo Dong, Liuyi Dang, Xinwen Zhang, Shisheng Sun*. Site-specific N-glycan changes during semen liquefaction. Analytical Biochemistry. 2023, 680: 115318.
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