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Professor
Supervisor of Doctorate Candidates
Supervisor of Master's Candidates

Paper Publications

An emerging paradigm to develop analytical methods based on immobilized transmembrane proteins and its applications in drug discovery[J].TrAC-Trends in Analytical Chemistry,2022,157(116728):
Covalent immobilization of beta2 adrenergic receptor through trans-methylation reaction by SNAP-tag and its application in anti-asthmatic compound screening from Raphani Semen[J].Journal of Pharmaceutical and Biomedical Analysis,2022,219(114952):
Preparation and characterization of immobilized 5-HT1A receptor stationary phase for high throughput screening of the receptor-binding ligands from complex systems like Curcuma wenyujin Y. H. Chen et C. Ling extract[J].Journal of Pharmaceutical and Biomedical Analysis,2022,211(114632):
Site-selective covalently immobilized alpha 1A adrenergic receptor for thermodynamic and extra-thermodynamic study of four ligands binding to the receptor by chromatographic methods[J].Journal of Chromatography A,2022,1665(462827):
Development of immobilized beta1-adrenoceptor chromatography for rapid discovery of ligands specifically binding to the receptor from herbal extract[J].Journal of Chromatography A,2022,1677(463298):
Screening of bioactive flavour compounds targeting muscarinic-3 acetylcholine receptor from Siraitia grosvenorii and evaluation of their synergistic anti-asthmatic activity[J].Food Chemistry,2022,395(133593):
Discovery of dual-target ligands binding to beta2-adrenoceptor and cysteinyl-leukotriene receptor for the potential treatment of asthma from natural products derived DNA-encoded library[J].European Journal of Medicinal Chemistry,2022,233(114212):
Early potential evaluation of lead compounds from a DNA-encoded library by the determination of their thermodynamics through a chromatographic method based on immobilized β2-adrenoceptor[J].Bioorganic & Medicinal Chemistry,2022,68(116864):
Development of an Allostery Responsive Chromatographic Method for Screening Potential Allosteric Modulator of Beta2-adrenoceptor from a Natural Product-Derived DNA-Encoded Chemical Library[J].Analytical Chemistry,2022,94(25):9048-9057
Identification of selective ligands targeting two GPCRs by receptor-affinity chromatography coupled with high-throughput sequencing techniquesBioorganic Chemistry,2021,112(104986):
Two-point immobilization of a conformation-specific beta2-adrenoceptor for recognizing the receptor agonists or antagonists inspired by binding-induced DNA assembly,Biomaterials Science,2021,9(7934):
Immobilized beta2-adrenergic receptor: a powerful chromatographic platform for drug discovery and evaluation of drug-like property for natural products[J]., Journal of Chromatography A,2021,1695(462635):

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