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影响因子：16.1

DOI码：10.1002/anie.202407757

发表刊物：Angew. Chem. Int. Ed.

摘要：17-nor-Cephalotane diterpenoids include two categories, Cephalotaxus troponoids and tropone-free 17-nor-cephalotane diterpenoids, which possess polycyclic frameworks with seven-membered A ring bearing different oxidation states. We report herein a novel ynoldiene cyclization as a rapid access to tropone unit. Combining with a bioinspired stereoselective dual hydrogenation, the first divergent strategy to both categories of 17-nor-cephalotane diterpenoids has been successfully established, which enabled the total synthesis of Cephalotaxus troponoids, (+)-3-deoxyfortalpinoid F and (+)-harringtonolide, and tropone-free 17-nor-cephalotane diterpenoids, (−)-fortalpinoids M/N/P and analog (−)-20-deoxocephinoid P, in 14-17 linear longest steps starting from commercially available materials.

论文类型：期刊论文

页面范围：e202407757

是否译文：否

收录刊物：SCI

发布期刊链接：https://onlinelibrary.wiley.com/doi/full/10.1002/anie.202407757

通讯作者：胡向东