个人简介：

理学博士，硕士研究生导师。研究方向集中在病原微生物生理学、分子微生物学及环境微生物学领域，主要从事病原微生物Ⅵ型分泌系统的环境适应性和应对宿主免疫应答机制，以及细菌致病性和耐药性机制研究。先后主持国家自然科学基金面上项目、青年科学基金项目；陕西省自然科学基础研究计划青年项目；中国博士后基金和陕西省博士后基金等科研项目。相关研究成果发表于Cell Reports, PloS Pathogens, Molecular Microbiology等高水平期刊，累计发表研究论文20余篇。

主持科研项目：

国家自然科学基金，面上项目，铜绿假单胞菌Ⅵ型分泌系统H1-T6SS的表达调控机制及新功能研究，2023.01-2026.12

陕西省科学技术厅，陕西省自然科学基础研究计划青年项目，铜绿假单胞菌Ⅵ型分泌系统H2-T6SS的表达调控机制研究，2022.01-2023.12

西北大学，科研启动基金，铜绿假单胞菌Ⅵ型分泌系统致病机制研究，2021.01-2023.12

国家自然科学基金，青年基金，铜绿假单胞菌Ⅵ型分泌系统钼转运及机制研究，2019.01-2021.12

中国博士后基金，一等资助，铜绿假单胞菌Ⅵ型分泌系统响应低氧条件的调控机制研究，2018.12-2020.10

陕西省博士后科研项目，二等资助，铜绿假单胞菌Ⅵ型分泌系统的铜转运研究，2018.11-2020.10

西北大学，师资博士后科研启动基金，铜绿假单胞菌Ⅵ型分泌系统功能研究，2018.03-2020.03

代表性学术论文：

Congcong Guan^#, Yi Huang^#, Yun Zhou, Yuqian Han, Shuhui Liu, Shimin Liu, Weina Kong*, Tietao Wang*, Yani Zhang*. FlhF affects the subcellular clustering of WspR through HsbR in Pseudomonas aeruginosa. Appl Environ Microbiol, 2024, 90(1):e0154823. 中科院二区，IF=4.4.

Hai Liu^#, Zhiyan Wei^#, Jiali Li, Xingyu Liu, Lingfang Zhu, Yao Wang, Tietao Wang*, Changfu Li* and Xihui Shen. A Yersinia T6SS Effector YezP Engages the Hemin Uptake Receptor HmuR and ZnuABC for Zn²⁺ Acquisition. Appl Environ Microbiol, 2023, 89(7):e0024023. 中科院二区，IF=4.4.

Meng Li, Nannan Guo, Gaoyu Song, Yi Huang, Lecheng Wang, Yani Zhang* and Tietao Wang*. Type II Toxin-Antitoxin Systems in Pseudomonas aeruginosa. Toxins, 2023, 15(2):164. 中科院二区，IF=4.2.

Jing Dang^#, Tietao Wang^#, Jing Wen and Haihua Liang*. An Important Role of the Type VI Secretion System of Pseudomonas aeruginosa Regulated by Dnr in Response to Anaerobic Environments. Microbiol Spectr, 2022, 10(6):e0153322. 中科院二区，IF=3.7.

Tietao Wang, Xiao Du, Linxuan Ji, Yuying Han, Jing Dang, Jing Wen, Yarong Wang, Qinqin Pu, Min Wu and Haihua Liang*. Pseudomonas aeruginosa T6SS-mediated molybdate transport contributes to bacterial competition during anaerobiosis. Cell Rep, 2021, 35(2):108957. 中科院一区, IF=9.995.

Hongying Jiao^#, Fan Li^#, Tietao Wang^#, Yam Joey Kuok Hoong, Liang Yang and Haihua Liang*. The Pyocin Regulator PrtR Regulates Virulence Expression of Pseudomonas aeruginosa by Modulation of Gac/Rsm System and c-di-GMP Signaling Pathway. Infect Immun, 2021, 89(2):e00602-20. 中科院三区, IF=3.616.

Tietao Wang^#, Yihang Qi^#, Zhihan Wang, Jingru Zhao, Linxuan Ji, Jun Li, Zhao Cai, Liang Yang, Min Wu and Haihua Liang*. Coordinated regulation of anthranilate metabolism and bacterial virulence by the GntR family regulator MpaR in Pseudomonas aeruginosa. Mol Microbiol, 2020, 114(5):857-869. 中科院二区, IF=3.501.

Tietao Wang^#, Zhaoyu Hu^#, Xiao Du, Yue Shi, Jing Dang, Mijoon Lee, Dusan Hesek, Shahriar Mobashery, Min Wu and Haihua Liang*. A Type VI secretion system delivers a cell-wall amidase to target bacterial competitors. Mol Microbiol, 2020, 114(2):308-321. 中科院二区, IF=3.501.

Zhuo Wang^#, Tietao Wang^#, Rui Cui, Zhenxing Zhang, Keqi Chen, Mengyun Li, Yueyue Hua, Huawei Gu, Lei Xu, Yao Wang, Yantao Yang* and Xihui Shen*. HpaR, the Repressor of Aromatic Compound Metabolism, Positively Regulates the Expression of T6SS4 to Resist Oxidative Stress in Yersinia pseudotuberculosis. Front Microbiol, 2020, 11:705. 中科院二区, IF=5.64.

Yuying Han^#, Tietao Wang^#, Gukui Chen, Qinqin Pu, Qiong Liu, Yani Zhang, Linghui Xu, Min Wu and Haihua Liang*. A Pseudomonas aeruginosa type VI secretion system regulated by CueR facilitates copper acquisition. PLoS Pathog, 2019, 15(12):e1008198. 中科院一区, IF=6.218.

Tietao Wang^#, Meiru Si^#, Yunhong Song^#, Wenhan Zhu, Fen Gao, Yao Wang, Lei Zhang, Weipeng Zhang, Gehong Wei, Zhao-Qing Luo and Xihui Shen*. Type VI Secretion System Transports Zn²⁺ to Combat Multiple Stresses and Host Immunity. PLoS Pathog, 2015, 11(7):e1005020. 中科院一区, IF=7.003.

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