Personal Information:

Professor


Supervisor of Doctorate Candidates


Supervisor of Master's Candidates

Date of Employment:2016-09-28

School/Department:生命科学学院

Administrative Position:副处

Education Level:With Certificate of Graduation for Doctorate Study

Business Address:科研楼11层东

Gender:Male

Degree:博士

Status:Employed

Alma Mater:中国农业大学

Discipline:Cell Biology
Biochemistry and Molecular Biology

Profile

关锋:西北大学生命科学学院副院长; 陕西省生物技术与生化工程重点实验室主任; 中国生物工程学会糖生物学工程分会副主任委员; 陕西省基础科学(化学、生物学)研究院副院长; 中国生物工程学会青年委员会委员; 中国细胞生物学青年委员会委员;西安市第九届委员会常委;生物学杂志编委;陕西省百人计划(长期项目),陕西省杰出青年计划入选者。

 

近年来代表性文章(IF>10):

1. Hongjiao Li, Yi Wang, Fenfang Yang, Shuang Feng , Kaijing Chang , Xinwen Yu, Feng Guan,  Xiang Li. Clonal MDS/AML cells with enhanced TWIST1 expression reprogram the differentiation of bone marrow MSCs. Redox Biology. 2023 Nov:67:102900. doi: 10.1016/j.redox.2023.102900. (共同通讯作者:IF=11.4

2. Feng J, Wang Y, Li B, Yu X, Lei L, Wu J, Zhang X, Chen Q, Zhou Y, Gou J, Li H, Tan Z, Dai Z, Li X, Guan F. Loss of bisecting GlcNAcylation on MCAM of bone marrow stoma determined pro-tumoral niche in MDS/AML. Leukemia. 2022 Nov 5. doi: 10.1038/s41375-022-01748-1.(通讯作者:IF=12.883

3. Tan Z, Jiang Y, Liang L, Wu J, Cao L, Zhou X, Song Z, Ye Z, Zhao Z, Feng H, Dong Z, Lin S, Zhou Z, Wang Y, Li X, Guan F. Dysregulation and prometastatic function of glycosyltransferase C1GALT1 modulated by cHP1BP3/ miR-1-3p axis in bladder cancer. J Exp Clin Cancer Res. 2022 Jul 21;41(1):228. (通讯作者:IF=11.16

4. Jinpeng Wu#, Zengqi Tan#, Hongjiao Li, Meixuan Lin, Yazhuo Jiang, Liang Liang, Qilong Ma, Junjie Gou, Lulu Ning, Xiang Li*, Feng Guan*. Melatonin reduces proliferation and promotes apoptosis of bladder cancer cells by suppressing O-GlcNAcylation of CDK5. Journal of Pineal Research. 2021 Sep 6;e12765. doi: 10.1111/jpi.12765.(通讯作者:IF=12.081

5. Z Tan, L Cao, Y Wu, B Wang, Z Song, J Yang, L Cheng, X Yang, X Zhou, Z Dai*, X Li*, F Guan*. Bisecting GlcNAc modification diminishes the pro-metastatic functions of small extracellular vesicles from breast cancer cells. J Extracell Vesicles. 2020;10:56-72.(通讯作者:IF=17.337

6. Li H, Wang Y, Pang X, Xie C, Deeg HJ, Wang H, Wan T, Wu J, Guan F*, Li X*.Elevated TWIST1 expression in myelodysplastic syndromes/ acute myeloid leukemia reduces efficacy of hypomethylating therapy with decitabine. Haematologica. 2020 Jan 30;105(10):235325. doi: 10.3324/haematol.2019.235325.(通讯作者:IF=11.047




Social Affiliations

Research Focus

Research Group

    1  Name of Research Group:肿瘤糖生物学

    Description of Research Group:组成生命的基本物质包括:4种核苷酸、20种基本氨基酸、8种脂肪酸和32单糖。细胞中具有生物学功能的糖以糖链形式存在,糖链与蛋白质或脂类相结合形成糖缀合物,包括糖鞘脂、糖蛋白、GPI锚定蛋白和蛋白聚糖等。生物...


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