研究领域

• 一、光学

  • 光学成像技术

  • 光谱分析技术

  • 光学信息分析与处理技术

  二、生物医学光子学

  • 光与生物组织相互作用

  • 生物光学检测技术

  • 生物光信息分析技术

  三、光谱学

  • 拉曼光谱分析技术

  • 荧光光谱分析技术

  • 光谱分析技术在生物医学中的应用
    

论文成果 More>>

• Confocal Raman microspectral analysis and imaging of the drug response of osteosarcoma to cisplatin .Analytical Methods ,2021 (13) :2527-2536
• Interpreting the biochemical speci¯city of mouse spinal cord by confocal raman microspectral imaging .Journal of Innovative Optical Health Sciences ,10 (5)
• Raman spectroscopic investigation on the biomedical evolution of spinal cord injury and the therapeutic outcomes of its low-level laser therapy .Vibrational Spectroscopy .2022 ,118
• Investigating the cellular responses of osteosarcoma to cisplatin by confocal Raman microspectroscopy .Journal of Photochemistry & Photobiology, B: Biology .2021 ,226
• 基于逆向空间偏移拉曼光谱技术的多层混浊样品深层分析研究 .光谱学与光谱分析 .2021 ,41 (11) :3456-3461
• Validating Multivariate Classification Algorithms in Raman Spectroscopy-Based Osteosarcoma Cellular Analysis .ANALYTICAL LETTERS .2021
• Unveiling osteosarcoma responses to DAPT combined with cisplatin by using confocal Raman microscopy .Biomedical Optics Express .2021 ,12 :5514-5528
• Studying the pathological and biochemical features in breast cancer progression by confocal Raman microspectral imaging of excised tissue samples .Journal of Photochemistry & Photobiology, B: Biology .2021
• NWU-RSIT: An integrated graphical user interface for biomedical Raman spectral imaging with both univariate and multivariate modules .JOURNAL OF RAMAN SPECTROSCOPY .2021
• Raman spectroscopy based pathological analysis and discrimination of formalin fixed paraffin embedded breast cancer tissue .Vibrational Spectroscopy .2021 ,115
• Raman Microspectral Study and Classification of the Pathological Evolution of Breast Cancer Using Both Principal Component Analysis-Linear Discriminant Analysis and Principal Component Analysis-Support Vector Machine .Journal of Spectroscopy .2021 ,2021
• Raman Microspectroscopic Investigation and Classification of Breast Cancer Pathological Characteristics .molecules .2021 ,26 (921)
• A graphical user interface (NWUSA) for Raman spectral processing, analysis and feature recognition .JOURNAL OF BIOPHOTONICS .2021
• Unveiling dose- and time-dependent osteosarcoma cell responses to the γ-secretase inhibitor, DAPT, by confocal Raman microscopy .JOURNAL OF BIOPHOTONICS .2020 ,2020 (13)
• Confocal Raman microspectroscopic analysis on the time-dependent impact of DAPT, a γ-secretase inhibitor, to osteosarcoma cells .Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy .2020
• Confocal Raman Spectral Imaging Study of DAPT, a γ-secretase Inhibitor, Induced Physiological and Biochemical Reponses in Osteosarcoma Cells .International Journal of Medical Sciences .2020 ,17 (5) :577-590
• Raman spectroscopy combined with multivariate analysis to study the biochemical mechanism of lung cancer microwave ablation .Biomedical Optics Express .2020 ,11
• Utilizing Raman spectral imaging for distinguishing breast cancer from hyperplasia .Eleventh International Conference on Information Optics and Photonics (CIOP 2019) .2019 ,11209
• Inverse spatially offest Raman spectroscopy and its applications sub-surface material detections .Eleventh International Conference on Information Optics and Photonics (CIOP 2019) .2019
• Study on the biochemical mechanisms of the micro-wave ablation treatment of lung cancer by ex vivo confocal Raman microspectral imaging .Analyst .2019

专利

• 拉曼光谱分析与成像软件V1.0
• 一种改进的拉曼光谱多元数据分析及成像方法
• 一种拉曼光谱多元数据分析方法
• 集拉曼光谱快速成像和深层光谱快速检测于一体的便携式光路系统
• 一种手持式皮肤癌变早期光学检测装置及其使用方法
• 一种逆向空间偏移拉曼光谱检测系统及方法
• 用于受激发射损耗显微镜的全保偏光纤激光点阵产生装置

著作成果

暂无内容

科研项目

• 共聚焦显微拉曼光谱成像仪器研发项目, 企事业单位委托科技项目 , 2023/10/30
• 基于近红外多模血糖光谱的糖尿病“未病”辨识方法研 究, 国家自然科学基金项目 , 2023/12/29
• 基于单分子光谱与成像技术的脊髓损伤与修复无损研究, 自然科学基础研究计划重点项目 -2018/12/01 , 结题 , 参与
• 基于显微拉曼光谱成像方法的人体皮肤癌变机理研究 , 2014/01/01
• 基于显微拉曼光谱成像技术的人体皮肤组织癌变机理研究 , 2014/01/01
• 共聚焦模式下的生物组织拉曼散射作用机理及其光谱信息重构研究 , 2014/01/01
• 生物组织共聚焦拉曼散射作用机理及其超分辨光谱信息重构研究 -2016/12/01 , 结题 , 参与
• 弱激光促脊髓损伤修复的生物光学作用机理研究, 自然科学基础研究计划面上项目 -2019/12/01 , 结题 , 主持
• 相干拉曼光谱显微成像技术及其在生物医学中的应用, 国家自然科学基金项目 -2021/02/28 , 结题 , 主持
• 远场光学超分辨成像技术研究DNA单分子穿越纳米通道的流动特性, 国家自然科学基金项目 , 在研 , 面上项目
• 电动力湍流中流动的间歇特性及能量级串的实验研究, 国家自然科学基金项目 -2020/12/31 , 结题 , 参与
• 光电子与纳米光子技术生物医学应用创新团队, 陕西省创新能力支撑计划 -2021/12/01 , 结题 , 参与