paper publications

113. JZ Chigan, ZX Hu, L Liu, YS Xu, HH Ding, KW Yang*, ''Quinolinyl sulfonamides and sulphonyl esters exhibit inhibitory efficacy against New Delhi metallo-β-lactamase-1 (NDM-1)'', Bioorg. Chem., 2022, 120, 105654.

 

112.  C Chen, KW Yang*, L Zhai, HH Ding, JZ Chigan, "Dithiocarbamates combined with copper for revitalizing meropenem efficacy against NDM-1-producing carbapenem-resistant Enterobacteriaceae", Bioorg. Chem., 2022, 118, 105474.

 

111.  JZ Chigan, JQ Li, HH Ding, YS Xu, L Liu, C Chen, KW Yang*, "Hydroxamates as a potent skeleton for the development of metallo-β-lactamase inhibitors", Chem Biol Drug Des., 2022, 99, 362-372.

110.  HH Ding, JZ Chigan, JB Zhen, L Liu, YS Xu, C Chen, KW Yang*, "Cholesteroled polymer (Chol-b-Lys)-based nanoparticles (CL-NPs) confer antibacterial efficacy without resistance", New J. Chem., 2021, 45, 20743-20750.

 

109.  H Gao, JQ Li, PW Kang, JZ Chigan, H Wang, L Liu, YS Xu, L Zhai*, KW Yang*, "N-acylhydrazones confer inhibitory efficacy against New Delhi metallo-β-lactamase-1", Bioorg. Chem., 2021, 114，105138.

 

108.  Y Ge†, PW Kang†, JQ Li, H Gao, LY Sun, C Chen, KW Yang*, "Thiosemicarbazones exhibit inhibitory efficacy against New Delhi metallo-β-lactamase-1 (NDM-1)", J. Antibiot., 2021,74，574-579.

 

107.  LY Sun, C Chen, JP Su, JQ Li, ZH Jiang, H Gao, JZ Chigan, HH Ding, L Zhai, KW Yang*,  "Ebsulfur and Ebselen as highly potent scaffolds for the development of potential SARS-CoV-2 antivirals", Bioorg.Chem., 2021, 112, 104889.

106.  JQ Li, H Gao, L Zhai, LY Sun, C Chen, JZ Chigan, HH Ding, KW Yang*, "Dipyridyl-substituted thiosemicarbazone as a potent broad-spectrum inhibitor of metallo-β-lactamases", Bioorg. Med. Chem., 2021, 38, 116128.

105. HH Ding, MH Zhao, L Zhai, JB Zhen, LY Sun, JZ Chigan, C Chen,  JQ Li, H Gao, KW Yang*, "Quinine-based quaternized polymer: A potent scaffold with bactericidal properties without resistance", Polymer Chemistry, 2021, doi:10.1039/D0PY01751E.

104. JQ Li, H Gao, L Zhai, LY Sun, C Chen, JZ Chigan, HH Ding, KW Yang*, "Dipyridyl-substituted thiosemicarbazone as a potent broad-spectrum inhibitor of metallo-β-lactamases", Bioorg. Med. Chem., 2021, accepted.

103. Y Ge, LW Xu, JB Zhen, C Chen, M Lv, JP Su, KW Yang*, Cheng-Cheng Liu*, "A degradation product from hydrolysate of imipenem with ImiS broad-spectrum inhibits metallo-β-lactamases",Jund. J. Microb., 2021, accepted.

102.  C Chen, KW Yang*, LY Wu, JQ Li, LY Sun, "Disulfiram as a potent metallo-β-lactamase inhibitor with dualfunctional mechanisms", Chem. Commun., 2020, 56, 2755-2758.

101.  C Chen†, Y Xiang†, KW Yang*, YJ Zhang, WM Wang, JP Su, Y Ge, Y Liu, "A protein structure-guided covalent scaffold selectively targets the B1 and B2 subclass metallo-β-lactamases", Chem. Commun., 2018, 54, 4802-4805.

100.  KW Yang†*, YJ Zhou†, Y Ge, YJ Zhang, "Real-time activity monitoring of New Delhi metallo-β-lactamase-1 in living bacterial cells by UV-Vis spectroscopy", Chem. Commun., 2017, 53, 8014-8017.

99.  XY Ouyang†*, YN Chang†, KW Yang†*, WM Wang, JJ Bai, JW Wang, YJ Zhang, SY Wang, BB Xie, LL Wang, "A DNA nanoribbon as a potent inhibitor ofmetallo-β-lactamases", Chem. Commun., 2017, 53, 8878-8881.

98.  C Chen and KW Yang*, "Structure-based design of covalent inhibitors targeting metallo-β-lactamases", Eur. J. Med. Chem., 2020, 203, 112573.

97.  C Chen, LY Sun, H Gao, PW Kang, JQ Li, JB Zhen, KW Yang*, "Identification of cisplatin and palladium(II) complexes as potent metallo-β-lactamases inhibitors for targeting carbapenem-resistant Enterobacteriaceae (CRE)", ACS Infect. Dis., 2020, 6, 975-985.

96.  YJ Zhang†, WM Wang†, P Oelschlaeger, C Chen, JE Lei, M Lv, KW Yang*, "Real-time monitoring of NDM-1 activity in live bacterial cells by isothermal titration calorimetry: a new approach to measure inhibition of antibiotic-resistant bacteria", ACS Infect. Dis., 2018, 4, 1671-1678.

95.  C Chen and KW Yang*, "Ruthenium complex as prospective inhibitor of metallo-β-lactamases to reverse carbapenem resistance", Dalton Trans., 2020, 49, 14099-14105.

94.  Y Xiang, YJ Zhang, Y Ge, YJ Zhou, C Chen, WX Yuan Wahlgren, XS Tan, X Chen, KW Yang*, "Kinetic, thermodynamic, and crystallographic studies of 2-triazolylthioacetamides as Verona Integron-Encoded metallo-β-lactamase 2 (VIM-2) inhibitor", Biomolecules, 2020, 10, 72.  

93.  Y Ge†, LW Xu†, Y Liu, LY Sun, H Gao, JQ Li, KW Yang*, "Dithiocarbamate as a valuable scaffold for the inhibition of metallo-β-Lactmases", Biomolecules, 2019, 9, 699.

92.  JB Zhen, PW Kang, MH Zhao, KW Yang*, "Silver nanoparticle conjugated star PCL-b-AMPs copolymer as nanocomposite exhibits efficient antibacterial properties", Bioconjugate Chem., 2020, 319, 51-63.

91.  JB Zhen, MH Zhao, Y Ge, Y Liu, LW Xu, C Chen, YK Gong, KW Yang*, "Construction, mechanism and antibacterial resistance insight of the polypeptide-based nanoparticles", Biomater. Sci., 2019, 7, 4142-4152.

90.  PW Kang†, JP Su†, LY Sun, H Gao, KW Yang*, "3-Bromopyruvate as a potent covalently reversible inhibitor of New Delhi metallo-β-lactamase-1 (NDM-1)", Eur. J. Pharm. Sci., 2020, 142, 105161.

89.  MH Zhao†, JB Zhen†, KW Yang*, Y Liu, JQ Li, SQ Shi, "Quaternized polymer-based nanostructures confer antimicrobial efficacy againstmultidrug-resistant bacteria", New J. Chem., 2020, 44, 3874-3881.

88.  Y Liu, C Chen, LY Sun, H Gao, JB Zhen, KW Yang*, "Meta-substituted benzenesulfonamide: a potent scaffold for thedevelopment of metallo-β-lactamase ImiS inhibitors", RSC Med. Chem., 2020, 11, 259-267.

87.  YL Zhang*, Y Yan, XJ Wang, KW Yang, "Synthesis and bioactivity of thiazolethioacetamidesas potential metallo-β-lactamase inhibitors", Antibiotics, 2020, 9, 99.

86.  YJ Zhang, L Zhai, Y Wan, KW Yang*, "Triazolylthioacetamides confer inhibitory efficacy against metallo-β-Lactamase IMP-1", Lett. Drug. Des. Discov., 2020, 17, doi: 10.2174/1570180817999200831094019.

85.  JQ Li, C Chen, M Yao, LY Sun, H Gao, JZ Chigan, KW Yang*, "Hydroxamic acid with benzenesulfonamide: an effective scaffold for the development of broad-spectrum metallo-β-lactamase inhibitors", Bioorg. Chem., 2020, doi: 10.1016/j.bioorg.2020.104436.

84.  H Gao, Y Ge, MH Jiang, C Chen, LY Sun, JQ Li, KW Yang*, "Real-time monitoring and inhibition of carbapenemase activity in live bacterial cells: application to screening of ß-lactamase inhibitors", New J. Chem., 2020, doi: 10.1039/D0NJ03475D.

83.  Y Ge†, PW Kang†, JQ Li, H Gao, LY Sun, C Chen, KW Yang*, "Thiosemicarbazones exhibit inhibitory efficacy against New Delhi metallo-β-lactamase-1 (NDM-1)", J. Antibiot., 2020, accepted.

82.  YX Li†, JB Zhen†, Q Tian, CQ Shen, LB Zhang, KW Yang, L Shang*, "One step synthesis of positively charged gold nanoclusters as effective antimicrobial nanoagents against multidrug-resistant bacteria and biofilms", J. Colloid. Interf. Sci., 2020, 569, 235-243.

81.  XR Wei, K Ma, YB Cheng, LY Sun, DJ Chen, XL Zhao, H Lu, BT Song, KW Yang, PX Jia*, "Adhesive, conductive, self-healing, and antibacterial hydrogel based on chitosan-polyoxometalate complexes for wearable strain sensor", ACS Appl. Polym. Mater., 2020, 2, 2541-2549.

80.  H Andersson, P Jarvoll, SK Yang, KW Yang, Máté Erdély*, "The binding mode of 2-(triazolylthio)acetamides to metallo-β-lactamase CcrA", ACS Omega., 2020, doi: 10.1021/acsomega.0c02187.

79.  C Chen and KW Yang*, "Ebselen bearing polar functionality: identification of potent antibacterial agents against multidrug-resistant Gram-negative bacteria", Bioorg. Chem., 2019, 93, 103286.

78.  JP Su, JY Liu, C Chen, YJ Zhang, KW Yang*, "Ebsulfur as a potent scaffold for inhibition and labelling of New Delhi metallo-β-lactamase-1 in vitro and in vivo", Bioorg. Chem., 2019, 84, 192-201.

77.  C Chen, Y Liu, YJ Zhang, Y Ge, JE Lei, KW Yang*, "The assemblage of covalent and metal binding dual functional scaffold for cross-class metallo-β-lactamases inhibition", Future Med. Chem., 2019, 11, 2381-2394.  

76.  M Lv, YJ Zhang, F Zhou, Y Ge, MH Zhao, Y Liu, KW Yang*, "Real-time monitoringof D-Ala-D-Ala dipeptidase activity of VanX in living bacteria by isothermal titration calorimetry", Anal. Biochem., 2019, 578, 29-35.  

75.  YL Zhang*, Y Yan, LF Liang, J Feng, XJ Wang, L Li, KW Yang, "Halogen-substituted triazolethioacetamides as a potent skeleton for the development of metallo-β-lactamase inhibitors", Molecules, 2019, 24, 1174.  

74.  Y Zhao, JL Wen, Y Ge, XT Zhang, H Shi, KW Yang, X Gao, SQ Shi*, YK Gong, "Fabrication of stable biomimetic coating on PDMS surface: cooperativity of multivalent interactions", Appl. Surf. Sci., 2019, 469, 720-730.  

73.  YJ Zhang, XL Liu, WM Wang, C Chen, MH Zhao, KW Yang*, "Amino acid thioesters exhibit inhibitory activity against B1-B3 subclasses of metallo-β-lactamases", Chem. Pharm. Bull., 2019, 67, 135-142.

72.  XL Liu†, Y Xiang†, C Chen, KW Yang*, "Azolylthioacetamides as potential inhibitors of New Delhi metallo-β-lactamase-1 (NDM-1)", J. Antibiot., 2019, 72, 118-121.

71.  Y Xiang†, C Chen†, WM Wang, LW Xu, KW Yang*, P Oelschlaeger, Y He, "Rhodanine as a poent scaffold for the development of broad-spectrum metallo-β-lactamase inhibitors" , ACS Med. Chem. Lett., 2018, 9, 359-364.

70.  C Chen†, Y Xiang†, Y Liu, XD Hu, KW Yang*, "Mercaptoacetate thioesters and their hydrolysate mercaptoacetic acid jointly inhibit metallo-β-Lactamase L1", MedChemComm, 2018, 9, 1172–1177.    

69.  T Yu, X Shu, KW Yang, XD Hu*, "Biomimetic total synthesis of ScabelloneB", Synlett., 2018, 29, 1617-1621.

68.  Q Wang†*, Y He†*, R Lu, WM Wang, KW Yang, HM Fan, Y Jin, GM Blackburn, "Thermokinetic Profile of NDM-1 and Its Inhibition by Small Carboxylic Acids", Bioscience Rep., 2018, 38 (2).

67.  YN Chang, Y Xiang, YJ Zhang, WM Wang, C Chen, P Oelschlaeger, KW Yang*, "Carbamylmethyl mercaptoacetate thioether: a novel scaffold for the development of L1 metallo-β-lactamase inhibitors", ACS Med. Chem. Lett., 2017, 8, 527-532.

66.  Y Xiang, YN Chang, Y Ge, JS Kang, YL Zhang, XL Liu, P Oelschlaeger, KW Yang*, "Azolylthioacetamides asa potent scaffold for the development of metallo-β-lactamase inhibitors", Bioorg. Med. Chem. Lett., 2017, 27, 5225-5229.

65.  Y Ge, YJ Zhou, KW Yang*, YL Zhang, Y Xiang, YJ Zhang, "Real-time activity assays of β-lactamases in living bacterial cells: application to the inhibition of antibiotic-resistant E. coli strains", Mol. BioSyst., 2017,13, 2323-2327.

64.  WJ Wang, Q Wang, Y Zhang, R Lu, YL Zhang, KW Yang*, JE Lei, Y He*, "Characterization of beta-lactamase activity using isothermal titration calorimetry", BBA-Gen. Subjects, 2017, 1861, 2031-2038.

63.  YL Zhang, YJ Zhang, WM Wang, KW Yang*, "Synthesis andinhibitory activity ofacetamidephosphonic acids against metallo-β-lactamases", Phosphorus Sulfur, 2017, 192, 14-18.

62.  L Zhai†, YL Zhang†, JS Kang, P Oelschlaeger, L Xiao, SS Nie,KW Yang*, "Triazolylthioacetamide: a valid scaffold for the development of New Delhi metallo-β-lactmase-1 (NDM-1) inhibitors", ACS Med. Chem. Lett., 2016, 7, 413-417.

61.  T Christopeit, KW Yang, SK Yang, HKS Leiros*, "The structure of the metallo-β-lactamase VIM-2 in complex with a triazolylthioacetamide inhibitor", Acta Crystallogr. F., 2016, 72, 813-819.  

60.  XL Liu, KW Yang*, YJ Zhang, Y Ge, Y Xiang, YNChang, P Oelschlaege, "Optimization of amino acid thioesters as inhibitors ofmetallo-β-lactamase L1", Bioorg. Med. Chem. Lett., 2016, 26, 4698-4701.

59.  LL Zhou, YQ Zhou, YL Tang, KW Yang,L Zhang, LX Gao,  GF Zhang, ZW Gao*, WQ Zhang*, "Antibacterial fischer carbenoid CO-releasing molecules (Fc-CORMs)", Chin. J. Org. Chem., 2016, 36, 2695-2703.

58.  XL Liu, Y Shi, JS Kang, P Oelschlaeger, KW Yang*, "Amino acid thioester derivatives: a highly promising scaffold for the development of metallo-β-lactamase L1 inhibitors", ACS Med. Chem. Lett., 2015, 6, 660–664.

57.  L Zhai and KW Yang*, "Porphyrin-vancomycin: a highly promising conjugate for the identification and photodynamic inactivation of antibiotic resistant Gram-positive pathogens", Dyes and Pigments, 2015, 120, 228-238.

56.  SK Yang, JS Kang, P Oelschlaeger, KW Yang*, "Azolylthioacetamide: a highly promising scaffold for the development of metallo-β-lactamase inhibitors", ACS Med. Chem. Lett., 2015, 6, 455-460.

55.  YL Zhang, KW Yang*, YJ Zhou, AE LaCuran, P Oelschlaeger, MW Crowder, "Diaryl-substituted Azolylthioacetamides: Inhibitor Discovery of New Delhi Metallo-β-Lactamase-1 (NDM-1)", ChemMedChem., 2014, 9, 2445-2448.

54.  X Yang, YJ Zhou, P He, YH Guo, CJ Liu, KW Yang*, "Activation free energy of Zn(II), Co(II) binding to metallo-β-lactamase ImiS", Chi. Chem. Lett., 2014, 25,1323-1326.

53.  KW Yang*, L Feng, SK Yang, M Aitha, AE LaCuran, P Oelschlaeger, MW Crowder*, "New β-phospholactam as a carbapenem transition state analog: synthesis of a broad-spectrum inhibitor of metallo-β-lactamases", Bioorg. Med. Chem. Lett., 2013, 23, 5855-5859.

52.  CC Liu, L Zhai, Y Shi, KW Yang*, "Purification of metallo-β-lactamase CcrA from Bacteroides fragilis with salting-out method", Braz. Arch. Biol. Technol., 2013, 56, 811-816.

51.  Y Shi, L Feng, Q Yang, YJ Zhou, Y Xiang, KW Yang*, "Thermokinetic evaluation of pyrrolidinedicarboxylic acid inhibiting cefalexinhydrolysis with metallo-β-lactamase L1 from  Stenotrophomonas  maltophilia", Thermochim. Acta, 2013, 563, 46-50.

50.  YL Zhang, JM Xiao, JL Feng, KW Yang*, L Feng, LS Zhou，MW Crowder*, "A novel fluorogenic substrate for dinuclear Zn(II)-containing metallo-β-lactamases", Bioorg. Med. Chem. Lett., 2013, 23, 1676-1679.

49.  L Zhai, LS Zhou, CC Liu, Y Shi, YJ Zhou, KW Yang*, "Determination of thermodynamic parametersof benzylpenicillinhydrolysis by metallo-β-lactamase CcrA from Bacteroides fragilis", Thermochim. Acta, 2013, 556, 54-57.

48.  LS Zhou, KW Yang*, L Feng, JM Xiao, CC Liu, YL Zhang, MW Crowder*, "Novel fluorescent risedronates: synthesis, photodynamic inactivation and imaging of Bacillus subtilis", Bioorg. Med. Chem. Lett., 2013, 23, 949-954.

47.  CC Liu, LS Zhou, JY Liu, JM Xiao, HZ Gao, KW Yang*, "Photoinactivation of vancomycin-resistant Enterococci and Bacillus subtilis by a novel norvancomycin-rhodamine B conjugate", New J. Chem., 2013, 37, 575-580.

46.  JM Xiao, L Feng, LS Zhou, HZ Gao, YL Zhang, KW Yang*, "Novel fluorescent cephalosporins: synthesis, antimicrobial activity and photodynamic inactivation of antibiotic resistant bacteria", Eur. J. Med. Chem., 2013, 59, 150-159.

45.  CC Liu, XB Zhao, KW Yang*, KZ Xu, L Zhai, X Yang, HZ Gao, "Exploring antibiotic resistance based on enzyme hydrolysis by microcalorimetry IV: determination of thermokinetic parameters of d-ala-d-ala hydrolysis with dipeptidase VanX", J. Therm. Anal. Calorim., 2013, 111, 1663-1667.

44.  L Zhai, KW Yang*, CC Liu, KZ Xu, X Yang, HZ Gao, Y Shi, L Feng, C Jia, LS Zhou, JM Xiao, "Exploring antibiotic resistance based on enzyme hydrolysis by microcalorimetry Ⅲ: determination of thermokinetic parameters of cefazolin hydrolysis with metallo-β-lactamase CcrA", J. Therm. Anal. Calorim., 2013, 111, 1657-1661.

43.  L Feng, KW Yang*, LS Zhou, JM Xiao, X Yang, L Zhai, YL Zhang, MW Crowder*, "N-heterocyclic dicarboxylic acids: broad-spectrum inhibitors of metallo-β-lactamases with Co-antibacterial effect against antibiotic-resistant bacteria", Bioorg. Med. Chem. Lett., 2012, 22, 5185-5189.

42.  L Zhai, KW Yang*, CC Liu, HZ Gao, X Yang, Y Shi, J Wen, "Thermokinetic characterization of imipenem hydrolysis with metallo-β-lactamase CcrA from Bacteroides fragilis", Thermochim. Acta, 2012, 539, 67-70.

41.  C Jia, KW Yang*, CC Liu, L Feng, JM Xiao, LS Zhou, YL Zhang, "Synthesis, characterization and activity of new phosphonate dipeptides as potential inhibitors of VanX", Bioorg. Med. Chem. Lett., 2012, 22, 482-484.

40.  X Yang, L Feng, KZ Xu, HZ Gao, C Jia, CC Liu, JM Xiao, L Zhai, LS Zhou, KW Yang*, "Exploring antibiotic resistant mechanism by microcalorimetry II: determination of thermokinetic parameters of imipenem hydrolysis with metallo-β-lactamase ImiS", J. Therm. Anal. Calorim., 2012, 110, 945-948.

39.  HZ Gao, Q Yang, XY Yan, ZJ Wang, JL Feng, X Yang, SL Gao, L Feng, X Cheng, C Jia, KW Yang*, "Exploring antibiotic resistant mechanism by microcalorimetry determination of thermokinetic parameters of metallo-β-lactamase L1 catalyzing penicillin G hydrolysis", J. Therm. Anal. Calorim., 2012, 107, 321-324.

38.  HZ Gao and KW Yang*, "Advances in the study of metallo-β-lactamases as drug-resistant target enzymes in superbugs", Chin. Pharm. J., 2012, 47, 325-330.

37.  HZ Gao, KW Yang*, XL Wu, JY Liu, L Feng, JM Xiao, LS Zhou, C Jia, Z Shi, "Novel conjugation of norvancomycin-fluorescein for photodynamicinactivation of Bacillus subtilis", ACS Bioconjugate Chem., 2011, 22, 2217-2221.

36.  KW Yang*, X Cheng, C Zhao, CC Liu, C Jia, L Feng, JM Xiao, LS Zhou, HZ Gao, X Yang, L Zhai, "Synthesis and activity study of phosphonamidate dipeptides as potential inhibitors of VanX", Bioorg. Med. Chem. Lett., 2011, 21, 7224-7227.

35.  XP Zhao, JH Zhan, XX Yan, KW Yang*, "Advances in the study of bisphosphonates", Chin. J. Osteoporos, 2011, 17, 917-921.

34.  XY Yan, HZ Gao, JL Feng, X Yang, L Feng, X Cheng, C Jia, KW Yang*, "Spectral characterization and kinetic study of WT-L1 and Co(II)-L1 catalyzing hydrolysis of β-lactam antibiotics", Chin. Antibiotic. J., 2011, 36, 388-393.

33.  JL Feng, X Yang, XY Yan, HZ Gao, L Feng, X Cheng, C Jia, D Wu, KW Yang*, "Kinetic study on expression and  purification of ImiS and catalyzing three group of β-lactams", Chin. Antibiotic. J., 2011, 36, 197-200.

32.  X Cheng, JL Feng, L Feng, KW Yang*, "Synthesis and activity determination of nitrocefin as MβLs test reagent", J. Northwest Uni. (Nat. Sci.), 2010, 40, 22-25.

31.  C Zhao, XY Yan, JL Feng, X Cheng, KW Yang*, "Synthesis and characterization of anti-osteoporosis drug sodium risedronate and its metal complex", J. Northwest Uni. (Nat. Sci.), 2010, 8, 1-7.

30.  C Zhao, XY Yan, JL Feng, X Cheng, KW Yang*, "Advances in the study of bisphosphonates anti-osteoporosis drugs", J. Northwest Uni. (Nat. Sci.), 2010, 40, 147-149.

29.  AL Costello, NP Sharma, KW Yang, MW Crowder*, DL Tierney, "X-ray absorption spectroscopy of the zinc-binding sites in the class B2metallo-b-lactamase ImiS from Aeromonas veronii bv. sobria", Biochemistry, 2006, 45, 13650-13658.

28.  NP Sharma, C Hajdin, S Chandrasekar, B Bennett, KW Yang, MW Crowder*, "Mechanistic studies on the mononuclear Zn(II)-containing metallo-β-lactamase ImiS from Aeromonas sobria", Biochemistry, 2006, 45, 10729-10738.

27.  AL Costello, G Periyannan, KW Yang, MW Crowder*, DL Tierney, "Site selective binding of Zn(II) to metallo-β-lactamase L1 from Stenotrophomonas Maltophilia", J. Biol. Inorg. Chem., 2006, 11, 351-358.

26.  GR Periyannan, AL Costello, DL Tierney, KW Yang, B Bennett, MW Crowder*, "Sequential binding of cobalt(II) to metallo-β-lactamase CcrA", Biochemistry, 2006, 45, 1313-1320.

25.  KW Yang, FC Golich, TK Sigdel, MWCrowder*, "Phosphinate, sulfonate andsulfonamidate dipeptides as potential inhibitors of aminopeptidase N", Bioorg. Med. Chem. Lett., 2005, 15, 5150-5153.

24.  PA Crawford, KW Yang, N Sharma, B Bennett, MW Crowder*, "Spectroscopic studies on Co(II)-substituted metallo-β-lactamase ImiS from Aeromonas veronii bv. sobria", Biochemistry, 2005, 44, 5168-5176.

23.  GPK Marasinghe, IM Sander, B Bennett, G Periyannan, KW Yang, CA Makaroff,MW Crowder*, "Structural studies on a mitochondrial glyoxalase II", J. Biol. Chem., 2005, 280, 40668-40675.

22.  KW Yang and MW Crowder*, "A method for removing ethylenediaminetetraacetic acid from apo-proteins", Anal. Biochem., 2004, 329, 342-344.

21.  KW Yang, DN Sobieski, AL Carenbauer, PA Crawford, CA Makaroff, MW Crowder*, "Explaining the inhibition of glyoxalase II by 9-Fluorenylmethoxycarbonyl-protected glutathione derivatives", Arch. Biochem. Biophys., 2003, 414, 271-278.

20.  MW Crowder*, KW Yang, AL Carenbauer, G Periyannan, ME Seifert, NE Rude, TR Walsh, "The problem of a solvent exposable disulfide when preparing Co(II)-substituted metallo-β-lactamase L1 from Stenotrophomonas maltophilia", J. Biol. Inorg. Chem., 2001, 6, 91-99.

19.  MW Crowder*, KW Yang, JJ Brandt, LL Chatwood, FC Golich, LA Detar, LR Herron, "Mechanistic and Inhibition Studies on VanX: The d-d-dipeptidase required for high level vancomycin resistance", Abstr. Pap. Am. Chem. Soc., 2001, 222, 197-INOR part 1.

18.  KW Yang, JJ Brandt, LL Chatwood, MW Crowder*, "Phosphonamidate and phosphothioate dipeptides as potential inhibitors of VanX", Bioorg. Med. Chem. Lett., 2000, 10, 1085-1087.

17.  KW Yang and MW Crowder*, "Inhibition studies on the metallo-β-lactamase L1 from Stenotrophomonas Maltophilia", Arch. Biochem. Biophys., 1999, 368, 1-6.

16.  JJ Brandt, LL Chatwood, KW Yang, MW. Crowder*, "Continuous assay for VanX, the d-ala-d-ala dipeptidase required for high-level vancomycin resistance", Anal. Biochem., 1999, 272, 94-99.

15.  MW. Crowder*, S McM-Munoz, AL Carenbauer, M Seifert, KW Yang, "Structure/function studies on metal-β-lactamase L1 from S. maltophilia", J. Inorg. Biochem., 1999, 74, 106.

14.  KW Yang, YZ Wang, ZX Huang*, J Sun, "Active site model of carbonic anhydrase: synthesis and crystal structure of functional tetrahedral zinc complex with hydrotris(3-phenyl-5-methylpyrazol-1-yl)borate", Polyhedron, 1997, 16, 109-112.

13.  KW Yang, YZ Wang, ZX Huang*, J Sun, "Synthesis, characterization and x-ray crystal structure of Zn(II) complex with poly-nitrogen ligand [(h3-HB(3,5-Me2pz)3]2Zn2C6H5CH3", Polyhedron, 1997, 16, 1297-1300.

12.  KW Yang*, YQ Yin, YZ Wang, ZX Huang, "Studies on synthesis, characterization and quantum chemistry of carbonic anhydrase active site model compounds [(h3-HB(3-Phpz)3ZnX] (X = Cl-, Br-, I- and NO3-)", Acta Chimia Sinica, 1997, 55, 209-214.

11.  KW Yang*, YQ Yin, ZX Huang, YH Wang, "Synthesis and crystal structure of zinc complex [Zn(P(py)3)2][Zn(NCS)4(MeCN)]", Polyhedron, 1996, 15, 79-81.

10.  KW Yang, YQ Yin*, DS Jin, "An active site model for carbonic anhydrase-synthesis and crystal structure of [(h3-HB(3-Phpz)3]ZnBr", Polyhedron, 1995, 14, 1021-1023.

9.  KW Yang, YQ Yin*, DS Jin, "Preparation of copper(I) complexes with novel pyrazolyl borates", Chi. Chem. Lett., 1994, 5, 341-342.

8.  KW Yang, JG Wu, LF Wang*, ZY Yang, "Determination of stability constants of rare earth(III) complexes by hypersensitive transition method", J. Lanzhou Uni. (Nat. Sci.), 1994, 30, 49-52.

7.  KW Yang, LF Wang*, JG Wu, F Dong, "Synthesis, characterization and antioxidative activity of new vitamin B6 triethanolamine rare earth(III) complexes", J. Inorg. Biochem., 1993, 52, 145-150.

6.  KW Yang, LF Wang*, JG Wu, ZY Yang, G Xiang, "Synthesis, characterization and antioxidative activity of vitamin B6 rare earth(III) complexes", J. Inorg. Biochem., 1993, 52, 151-155.

5.  KW Yang, JG Wu, LF Wang*, F Dong, "Determination of stability constants of Nd(III) complexes with pantothenate by absorption spectroscopy", Chi. J. Inorg. Chem., 1993, 9, 271-274.

4.  ZY Yang, LF Wang*, JG Wu, KW Yang, Y Zhu, "Studies on synthesis, characterization and electrical conductivity of the complexes of 3d transition metal with 2-oxo-propionic acid (4-pyridinecarbonyl) hydrazone", Acta Chimia Sinica, 1993, 51, 184-190.

3.  LF Wang*, KW Yang, JG Wu, "Determination of thermodynamical functions of neodymium pyridoxol complexes by hypersensitive transition method", Chi. J. Appl. Chem., 1993, 10, 84-86.

2.  ZY Yang, J Ai, LF Wang*, JG Wu, KW Yang, "Studies on the synthesis characterization and antitumor activity of the temary complexes of rare earth(III) with schiff base", J. Lanzhou Uni. (Nat. Sci.), 1993, 29, 162-166.

1.  ZY Yang, LF Wang*, JG Wu, XY Li, KW Yang, Q Wu, "Studies on anticancer activity of some rare earth (III) complexes with schif base", Chi. Sci. Bull., 1992, 9, 813-816.