陈卓玥，副教授，博士生导师。2016年于西北大学生命科学学院获得博士学位，2019年师资博士后出站留校任教。现任中国医促会骨科生物材料学部分会委员。曾于2019年至2022年在耶鲁大学病理系与Kyriakides Themis教授合作研究糖尿病溃疡、肢端坏疽的治疗修复策略。现主要研究方向为：构建新型可用于生物医药的重组融合蛋白并探究其作用机制（涉及到计算机、分子生物学、细胞生物学、生物医学）。在Acta biomaterialia，Journal of Controlled Release，Bioactive Materials，Advanced Science, Materials Today Bio,  J Adv Res., ACS Appl Mater Inter，等期刊发表研究论文20余篇；获授权发明专利4项。主持国家自然科学基金面上项目和青年项目各1项，国家博士后科学基金1项，陕西省教育厅自然科学专项课题1项。2022年入选陕西省高校第五批“青年杰出人才支持计划”。

工作经历：

2023.02- 今 ，西北大学生命科学与医学部 副教授

2019.06-2023.01 ，西北大学生命科学与医学部 讲师

2019.11-2022.01，耶鲁大学病理学系 访学

2017.01-2019.06 西北大学生命科学与医学部 师资博士后

2012.09-2016.12  西北大学生命科学学院 细胞生物学 博士

2009.09-2012.06  西南交通大学  生物医学工程 硕士（推免）

2005.09-2009.06  重庆大学  生物工程 本科

主持纵向科研项目：

（1）国家自然科学基金面上项目(新型RADA16-类人胶原融合材料的制备及其快速止血和促进组织修复性能的研究，2022.1-2025.12，32171329，58万)

（2）国家自然科学基金青年项目(重组类人胶原-骨形成蛋白融合材料的制备及其诱导成骨作用的研究，2018.1-2020.12，21706212，26万)

（3）中国博士后科学基金面上项目（基因重组类人胶原蛋白作为骨形成蛋白缓释载体的研究，2018.1-2019.6，2017M623228，5万）

（4）陕西省教育厅自然科学专项课题（新型类弹性蛋白-蚕丝纤维复合材料制备的研究，2016.7-2018.12，16JK2245，2万）

（5）陕西省高校第五批“青年杰出人才支持计划” 363032401023，2022（5万）中共陕西省委教育工委

发表文章

2026年

(1)   Jiake Zhang, Yuhan Xia , Xueliang Peng , Wenjing Li , Yuzhen Zhao , Fulin Chen, Zhuoyue Chen*, Vitronectin-GM-CSF Fusion Protein Hydrogel with a Recruitment-Anchoring-Activation Strategy Accelerates Vascularized Tissue Regeneration, Regenerative Biomaterials, 2026. https://doi.org/10.1093/rb/rbag100 (新锐分区一区TOP, IF>8)

2025年

(1)   Xueliang Peng#, Yijie Wang#, Shuyun Liu, Jiake Zhang, Ling Liu, Qian Liu, Xuanyi Li, Fulin Chen, Zhuoyue Chen*, Elastin-like polypeptide and triclosan-modified PCL membrane provides aseptic protection in tissue regeneration, Materials Today Bio, 2025, 33, 101968 (中科院一区top, 10.2)

(2)   Xueliang Peng#, Xuanning Chen#, Yifan Zhang, Zhichao Tian, Meihua Wang, Zhuoyue Chen*. Advances in the pathology and treatment of osteoarthritis. J Adv Res. 2025 Jan 30: S2090-1232(25)00072-4(中科院一区top, 13.0)

(3)   Zhuoyue Chen*, Rongrong Wang, Jing He, Qian Liu, Yifan Zhang, Yijie Wang, Ling Liu, Mingming Song, and Fulin Chen* A Recombinant Human Collagen and RADA-16 Fusion Protein Promotes Hemostasis and Rapid Wound Healing, ACS Appl. Bio Mater. 2025, 8, 236−251

(4)   Yayuan Guo, Xueliang Peng, Bin Cao, Qian Liu, Shen Li, Fulin Chen, Dalong Zhi, Shequn Zhang*, Zhuoyue Chen, A bilayer scaffold of collagen and nano-hydroxyapatite promotes osteochondral defect repair in rabbit knee joints, Bone Joint Res., 2025;14(2):155–165.

(5)   Qian Liu#, Jiawei Wu#, Ho-Pan Bei, Yufei Chen, Yifan Zhang, Xueliang Peng, Fulin Chen,Xin Zhao*,Zhuoyue Chen*, RADA16 and SAAP148 Peptide-Modified Collagen Self-Assembled Hydrogels for Accelerated Healing of Infected Wounds, Advanced Science, 2025, e19504 (中科院一区top, 14)

2024年

(1)   Zhuoyue Chen, Junqi Zhang, Francis Y. Lee, Themis R. Kyriakides*. Bone-derived extracellular matrix hydrogel from thrombospondin-2  knock-out mice for bone repair. Acta Biomaterialia 186(2024)85-94. (中科院一区top, 9.6)

(2)   Zhuoyue Chen, Yaqing Huang, Hao Xing, Tiffany Tseng, Hailey Edelman, Rachel Perry, Themis R. Kyriakides*. Novel muscle-derived extracellular matrix hydrogel promotes angiogenesis and neurogenesis in volumetric muscle loss. Matrix Biology 127 (2024) 38–47. (中科院一区TOP)

2023年

(1)   Qian Liu#, Xueliang Peng#, Xiaojia Liu, Xiaohui Mou, Yayuan Guo, Lihua Yang, Yufei Chen, Yaying Zhou, Zhuoya Shi, Zhilu Yang*, Zhuoyue Chen*. Advances in the application of bone morphogenetic proteins and their derived peptides in bone defect repair. Composites Part B., 2023, 262(2023):110805. (中科院一区top, >10)

(2)   Yayuan Guo#, Zeyu Hu#, Jilong Chen,Zhen Zhang, Qian Liu, Juan Li, Jiaojiao Yang, Zihan Ma, Jing Zhao, Jingyan Hu, Jiawei Wu, Zhuoyue Chen*. Injectable TG-linked recombinant human collagen hydrogel loaded with bFGF for rat cranial defect repair. Int J Biol Macromol., 2023, 236(2023):123864.

2022年前

(1)   Yayuan Guo, Nanqiong Cheng, Hongxiao Sun, Jianing Hou, Yuchen Zhang, Du Wang, Wei Zhang, Zhuoyue Chen*. Advances in the development and optimization strategies of the hemostatic biomaterials. Front Bioeng Biotechnol., 2022; 10: 1062676.

(2)   Zhuoyue Chen; Zhen Zhang; Zhaoyue Wang; Jiawei Wu; Yihang Wang; He Si; Xin Xie; Lijun Shang*; Daidi Fan*; Fulin Chen*; Fabricating a novel HLC-hBMP2 fusion protein for the treatment of bone defects, Journal of Controlled Release, 2021, 329: 270-285. (中科院一区top)

(3)   Zhuoyue Chen; Qiang Zhang; Hongmin Li; Qi Wei; Xin Zhao*; Fulin Chen*, Elastin-like polypeptide modified silk fibroin porous scaffold promotes osteochondral repair, Bioactive Materials, 2021, 16(3): 589-601. (中科院一区top)

(4)   Yayuan Guo, Zhengyue Bian, Qian Xu, Xiaomin Wen, Juan Kang, Shuai Lin, Xue Wang, Zhaoxiang Mi, Jihong Cui, Zhen Zhang, Zhuoyue Chen *, Fulin Chen*. Novel tissue-engineered skin equivalent from recombinant human collagen hydrogel and fibroblasts facilitated full-thickness skin defect repair in a mouse model. Mater Sci Eng C Mater Biol Appl. 2021, 130:112469.

(5)   Zhuoyue Chen; Daidi Fan*; Lijun Shang*; Exploring the potential of the recombinant human collagens for biomedical and clinical applications: a short review, Biomedical Material, 2020, 16: 012001.

(6)   Zhuoyue Chen; Zhen Zhang; Xiaoxuan Ma; Zhiguang Duan; Junfeng Hui; Chenhui Zhu; Donggang Zhang; Daidi Fan*; Lijun Shang*; Fulin Chen*; Newly Designed Human-Like Collagen to Maximize Sensitive Release of BMP-2 for Remarkable Repairing of Bone Defects, Biomolecules, 2019, 9: 450.

(7)   Rongrong Wang, Zhaoyue Wang, Yayuan Guo, Hongmin Li, Zhuoyue Chen*, Design of a RADA16-based self-assembling peptide nanofiber scaffold for biomedical applications, Journal of biomaterials science-polymer edition, 2019, 30(9): 713-736.

(8)   Zhuoyue Chen, Zhen Zhang, Juantao Feng, Yayuan Guo, Yuan Yu, Jihong Cui, Hongmin Li, Lijun Shang*, The influence of Mussel-Derived Bioactive BMP-2 decorated PLA on MSCs behavior in vitro and verification with osteogenicity at ectopic sites in vivo, ACS Appl Mater Inter, 2018, 10: 11961-71.

(9)   Zhuoyue Chen^#, Yue Song^#, Jing Zhang, Wei Liu, Jihong Cui*, Hongmin Li, Fulin Chen, Laminated electrospun nHA/PHB-composite scaffolds mimicking bone extracellular matrix for bone tissue engineering, Materials Science & Engineering C Materials for Biological Applications, 2017, 72(1):341-351.

(10)  Zhuoyue Chen^#, Jing Wei^#, Jun Zhu, Wei Liu, Jihong Cui, Hongmin Li, Fulin Chen*, Chm-1 gene-modified bone marrow mesenchymal stem cells maintain the chondrogenic phenotype of tissue-engineered cartilage, Stem Cell Research & Therapy, 2016, 7(1): 70. (中科院二区top)

(11)  Zhuoyue Chen*, Quanli Li, Jialong Chen, Rifang Luo, Manfred F. Maitz, Nan Huang*, Immobilization of serum albumin and peptide aptamer for EPC on polydopamine coated titanium surface for enhanced in-situ self-endothelialization, Materials Science & Engineering C Materials for Biological Applications, 2016, 60(1): 219-229.

(12)  Yayuan Guo, Bing Xu, Yihang Wang, Yan Li, He Si, Xiaoyan Zheng, Zhuoyue Chen, Fulin Chen*, Daidi Fan*. Dramatic promotion of wound healing using a recombinant human-like collagen and bFGF cross-linked hydrogel by transglutaminase. J Biomater Sci Polym Ed. 2019, 30(17):1591-160.

(13)  Jialong Chen, Juan Wang, Pengkai Qi, Xin Li, Baolong Ma, Zhuoyue Chen, Quanli Li, Yuancong Zhao, Kaiqin Xiong, Manfred F. Maitz, Nan Huang*, Biocompatibilitystudies of poly(ethylene glycol)-modified titanium for cardiovascular devices, Journal of Bioactive and Compatible Polymers, 2012, 27(6): 565-584.

(14)Jialong Chen, Cheng Chen, Zhuoyue Chen, Junying Chen, Quanli Li*, Nan Huang*, Collagen/heparin coating on titanium surface improves the biocompatibility of titanium applied as a blood-contacting biomaterial, J Biomed Mater Res A, 2010, 95(2): 341-349.

发明专利：

(1)陈卓玥; 陈富林; 侯增淼; 梁强; 赵金礼 ; 一种RHC-(RADA)4融合蛋白, 2022-11-01, 中国, ZL201910375539.8

(2) 陈富林; 陈卓玥; 李红民; 谢鑫; 崔继红; 余源; 张婧 ; 一种类弹性蛋白-蚕丝纤维多孔复合材料及其应用, 2019-6-4, 中国, ZL 201710024586.9

(3) 陈富林; 郭亚媛; 陈卓玥; 崔继红 ; 一种重组人胸腺肽多倍体蛋白水凝胶材料及其制备方法, 2025-2-20, 中国, CN202310207268.1

(4) 黄楠; 陈卓玥; 陈佳龙; 李全利; 王进; 冷永祥; 杨苹; 陈俊英; 孙鸿; 吴熹 ; 一种心血管植入装置表面固定多肽适配子的方法, 2011-6-8, 中国, CN201010589076.4

(5) 黄楠; 陈佳龙; 王娟; 李全利; 曹建军; 陈卓玥; 熊开琴; 孙鸿; 杨苹; 冷永祥; 陈俊英; 王进 ; 一种用于冠心病检测和治疗的纳米磁性粒子的制备方法, 2011-6-8, 中国, CN201110000852.7

(6) 陈卓玥; 刘倩; 朋学亮; 陈富林 ; 一种COL I/RADA-16/SAAP-148复合材料、制备方法及其应用, 2024-07-05, 中国, CN202410899111.4

(7) 陈卓玥; 朋学亮; 陈富林; 一种负载重组人弹性蛋白、槲皮素及三氯生的新型多功能可吸收手术缝合线 2024-06-26, 中国, CN202410834671.1

(8) 朋学亮; 刘倩; 赵之晗; 陈卓玥; 崔继红; 陈富林 ; 一种基于胶原蛋白和软骨形成蛋白的融合蛋白的水凝胶的制备方法及应用, 2023-09-07, 中国, CN202311149423.5