郭鹏琦
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郭鹏琦,西北大学制药工程专业副教授,硕士生导师。
招生方向主要包括生物与医药专业硕士(制药工程)、材料与化工专业硕士(化学工程)、化学工程与技术硕士(制药工程)
先后主持国家自然科学基金项目“基于转运体脂筏的蒽环心肌病高稳定药物筛选方法的建立及理论研究”(82304445);陕西省自然科学基金项目“低壁垒、双靶向治疗药物在线监测新方法的建立及理论基础研究”(2023-JC-YB-672)、“‘宽覆盖’中药潜在肝毒性皂苷类组分分析模型的建立及评价”(2020JQ-609);中国博士后科学基金项目“双靶标中药活性成分抗蒽环心脏毒性药物筛选模型的建立及其理论基础研究”(2020M683701XB);
参与国家自然科学基金项目“青霉素类抗生素中高分子杂质识别方法的建立与应用”(81173024);“天然药物中目标物快速‘识别鉴定’二维色谱仪研制”(81227802);“基于OATs转运蛋白和DNA嘌呤加合物的中药肾毒性分析模型的建立与评价”(81573391);陕西省中医药管理局项目“中药制剂中非法添加物的快速分析方法的建立与应用”(15ZY027)等科研项目,澳门科学技术发展基金项目“一种基于纳米酶-分子印迹-量子探针技术的有机磷农药残留快速灵敏检测体系的构建”。
发表论文:
[1] Fanru Zhong, Ranran Sun, Saipeng Huang, Pengqi Guo*, Qian Li, Lixia Wang, Hongxia Sun**, Li Yao. Determination of ligand selectivity to G-tetrad through an AMCA fluorescence quenching approach. Talanta, 2024, 280: 126732.
[2] Pengqi Guo*, Mingyang Xu, Fanru Zhong, Chenming Liu, Xia Cui, Jing Zhang, Min Zhao, Ziwei Yang, Liru Jia, Chuanming Yang, Weiming Xue, Daidi Fan*. Molecularly imprinted solid-phase extraction combined with non-ionic hydrophobic deep eutectic solvents dispersed liquid-liquid microextraction for efficient enrichment and determination of the estrogens in serum samples. Talanta, 2024, 269: 125480.
[3] Pengqi Guo*, Chenming Liu, Fanru Zhong, Mingyang Xu, Yongze Zhao, Xinya Xu, Yu Zhao, Weiming Xue, Ying Xu, Daidi Fan*. Dummy-template Pickering emulsion imprinted microspheres online pretreatment and analysis for the estrogens in cosmetics [J]. Journal of Chromatography A, 2023, 1691: 463815.
[4] Pengqi Guo*, Fanru Zhong, Yongze Zhao, Xinya Xu, Weiming Xue, Yichen Wang, Xiaoping Song, Weili Tang, Daidi Fan*. Thermosensitive molecularly imprinted polymer coupled with HPLC for selective enrichment and determination of matrine in traditional Chinese medicine. Journal of Chromatography B, 2022, 1191: 123130.
[5] Pengqi Guo, Wu Yang, Hao Hu, Yitao Wang, Peng Li*. Rapid detection of aflatoxin B1 by dummy template molecularly imprinted polymer capped CdTe quantum dots. Analytical and Bioanalytical Chemistry, 2019, DOI: 10.1007/s00216-019-01708-2.
[6] Pengqi Guo, Guoning Chen, Hua Shu, Peng Li, Pei Yu, Chun Chang, Yitao Wang, Qiang Fu*, Monodisperse molecularly imprinted microsphere cartridges coupled with HPLC for selective analysis of dexamethasone and hydrocortisone in cosmetics by using matrix solid-phase dispersion. Analytical Methods, 2019, 11: 3687-3696.
[7] Pengqi Guo, Zhimin Luo, Xinya Xu, Yulan Zhou, Bilin Zhang, Ruimiao Chang, Wei Du, Chun Chang and Qiang Fu*, Development of molecular imprinted column-on line-two dimensional liquid chromatography for selective determination of clenbuterol residues in biological samples. Food Chemistry, 2017, 217: 628–636.
[8] Pengqi Guo, Xinya Xu, Guoning Chen, Kamran Bashir, Hua Shu, Yanhui Ge, Wanghui Jing,Zhimin Luo, Chun Chang and Qiang Fu*, On-Line two dimensional liquid chromatography based on skeleton type molecularly imprinted column for selective determination of sulfonylurea additive in Chinese patent medicines or functional foods. Journal of Pharmaceutical and Biomedical Analysis, 2017, 146: 292–301.
[9] Pengqi Guo, Xinya Xu, Liang Xian, Yanhui Ge, Zhimin Luo, Wei Du, Wanghui Jing, Aiguo Zeng, Chun Chang and Qiang Fu*, Development of molecularly imprinted column-on line-two dimensional liquid chromatography for rapidly and selectively monitoring estradiol in cosmetics. Talanta, 2016, 161: 830–837.
[10] Yutao Zheng, Pengqi Guo, Fengyuan Yong, Renhui Wang, Jinglong Han, Yanxin Zhang, Huajie Chen, Kui Wang, Huiyun Wen, Shiyin Pan, Hua Yang, Chunting Wang, Saipeng Huang*, Weiming Xue*. Fabrication of amino-capped Pluronic F127 with aldehyde dextran chains: A strategy improving extensibility, compressibility and self-healing hydrogel for wound healing. International Journal of Biological Macromolecules, 2025, 304: 140774.
[11] Xinya Xu*, Yundong Xie, Pengqi Guo, Yongheng Shi, Meng Sun, Jing Zhou, Chuan Wang, Chaojun Han, Jiping Liu, Ting Li. Facile synthesis of novel helical imprinted fibers based on zucchini-derived microcoils for efficient recognition of target protein in biological sample. Food Chemistry, 2023, 404: 134645.
[12] Bo Cao, Cunjin Wang, Pengqi Guo, Qun Zhang, Chunting Wang, Hanhan Sun, Huiyun Wen, Xin Chen, Yaru Wang, Yao Wang, Saipeng Huang*, Weiming Xue*. Photo-crosslinked enhanced double-network hydrogels based on modified gelatin and oxidized sodium alginate for diabetic wound healing [J]. International Journal of Biological Macromolecules, 2023, 245: 125528.
[13] Enmin Wang, Huiyun Wen, Pengqi Guo, Yane Luo, Cunjin Wang, Zhi He, Junxue Pan, Xin Chen, Bo Cao, Yaru Wang, Saipeng Huang*, Weiming Xue*. Fabrication of methacrylated casein/alginate microspheres crosslinked by UV light coupled with Ca2+ chelation for pH‑sensitive drug delivery. Colloid and Polymer Science. 2022, 300: 553-567.
[14] Xinya Xu, Pengqi Guo, Hua Shu, Kenan Qu, Yanhui Ge, Guoning Chen, Zhimin Luo, Wei Du, Chun Chang, Ruilin Liu, Qiang Fu*. Preparation of biocompatible molecularly imprinted film on biowastederived magnetic pomegranate rind carbon for protein recognition in biological sample. Materials Science & Engineering C, 2020, 115: 111063.
[15] Kamran Bashir, Pengqi Guo, Guoning Chen, Yunzhe Li, Yanhui Ge, Hua Shu, Qiang Fu*. Synthesis, characterization, and application of griseofulvin surface molecularly imprinted polymers as the selective solid phase extraction sorbent in rat plasma samples. Arabian Journal of Chemistry, 2020, 13: 4082-4091.
[16] Guoning Chen, Pengqi Guo, Yan Wang, Lu Wang, Hua Shu, Yunzhe Li, Wanghui Jing, Chun Chang, Qiang Fu*. Preparation of molecularly imprinted polymers and application in a biomimetic biotin-avidin-ELISA for the detection of bovine serum albumin. Talanta, 2019, 198: 55-62.
[17] Wei Du, Bilin Zhang, Pengqi Guo, Guoning Chen, Chun Chang, Qiang Fu*. Facile preparation of magnetic molecularly imprinted polymers for the selective extraction and determination of dexamethasone in skincare cosmetics using HPLC. Journal of Separation Science, 2018, 41: 2441-2452.
[18] Wei Du, Min Sun, Pengqi Guo, Chun Chang, Qiang Fu*. Molecularly imprinted membrane extraction combined with high-performance liquid chromatography for selective analysis of cloxacillin from shrimp samples [J]. Food Chemistry, 2018, 259: 73-80.
[19] Hua Shu, Yanhui Ge, Xinya Xu, Pengqi Guo, Zhimin Luo, Wei Du, Chun Chang, Ruilin Liu, Qiang Fu*. Hybrid-type carbon microcoil-chitosan composite for selectiveextraction of aristolochic acid I from Aristolochiaceae medicinal plants. Journal of Chromatography A, 2018, 1561: 13-19.
[20] Xinya Xu, Ruilin Liu, Pengqi Guo, Zhimin Luo, Xiang Cai, Hua Shu, Yanhui Ge, Chun Chang, Qiang Fu*. Fabrication of a novel magnetic mesoporous molecularly imprinted polymer based on pericarpium granati-derived carrier for selective absorption of bromelain. Food Chemistry, 2018, 256: 91-97.
[21] Xinya Xu, Pengqi Guo, Zhimin Luo, Yanhui Ge, Yulan Zhou, Ruimiao Chang, Wei Du, Chun Chang and Qiang Fu*, Preparation and characterization of surface molecularly imprinted films coated on multiwall carbon nanotubes for recognition and separation of lysozyme with high binding capacity and selectivity. RSC Advances, 2017, 7: 18765-18774.
[22] Yanhui Ge, Pengqi Guo, Xinya Xu, Guoning Chen, Xuemei Zhang, Hua Shu, Bilin Zhang, Zhimin Luo, Chun Chang and Qiang Fu*. Selective analysis of aristolochic acid I in herbal medicines by dummy molecularly imprinted solid-phase extraction and HPLC. Journal of Separation Science. 2017, 40(13):2791-2799.
[23] Weiwei Wang, Zhimin Luo, Pengqi Guo, Huiyan Zhou, Qiang Fu* and Chun Chang, Selective preconcentration of mezlocillin from eggs by molecularly imprinted polymers on silica. Analytical Letters, 2017, 50(8): 1276-1291.
[24] Weili Tang, Wei Du, Pengqi Guo, Ningli Wu, Kangli Du, Changgen Xu, Zhimin Luo, Ruimiao Chang, Aiguo Zeng, Wanghui Jing, Chun Chang, Ji Li and Qiang Fu*, Molecularly Imprinted Solid Phase Extraction using bismethacryloyl β-cyclodextrin and Methacrylic Acid as Double Functional Monomers for Selective Analysis of Glycyrrhizic Acid in Aqueous Media. Journal of Chromatographic Science 2016, 54: 1-8.
[25] Zhimin Luo, Hua Shu, Pengqi Guo, Penglei Zheng, Xiaoyan Pan, Wei Du, Ruilin Liu, Aiguo Zeng, Chun Chang and Qiang Fu*, Study of the allergenic benzypenicilloyl–HSA and its specific separation from human plasma by a predesigned hybrid imprinted membrane. RSC Advances, 2016, 6: 15549-15557.
[26] Kangli Du, Zhimin Luo, Pengqi Guo, Weili Tang, Ningli Wu, Penglei Zheng, Wei Du, Aiguo Zeng, Wanghui Jing, Chun Chang and Qiang Fu*, Preparation and evaluation of a molecularly imprinted sol–gel material as the solid-phase extraction adsorbents for the specific recognition of cloxacilloic acid in cloxacillin. Journal of Separation Science, 2016, 39: 483-489.
[27] Zhimin Luo, Wei Du, Pengqi Guo, Penglei Zheng, Ruimiao Chang, Jin Wang, Aiguo Zeng, Chun Chang and Qiang Fu*, A porous hybrid imprinted membrane for selectively anchoring target proteins from a complex matrix. RSC Advances, 2015, 5: 72610-72620.
邮箱 :
[1]
2012.9 -- 2018.9
西安交通大学
 药物分析
 博士研究生毕业
 医学博士学位
[2]
2008.9 -- 2012.7
西北大学
 制药工程
 大学本科毕业
 工学学士学位
[1]
2018.9 -- 至今
西北大学
化工学院
副教授
[2]
2017.4 -- 2018.4
澳门大学
中华医药研究院
Research Assistant