Yani Zhang

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Professor  
Supervisor of Master's Candidates  

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    分子微生物学博士,教授,硕士生导师,生命科学学院副院长。主要从事病原微生物耐药性机理、抗氧化系统对病原菌致病性影响的研究。主持参与国家自然科学基金、厅部局项目多项。主讲遗传学课程,主持并完成多项教学项目,出版教材一部。

 

1.    Guan Congcong, Huang Yi, Zhou Yun, Han Yuqian, Liu Shuhui, Liu Shimin, Kong Weina*, Wang Tietao*, Zhang Yani*. FlhF affects the subcellular clustering of WspR through HsbR in Pseudomonas aeruginosa. Appl Environ Microbiol, 2023 Dec 19:e0154823. doi: 10.1128/aem.01548-23 .

2.     Meng Li, Nannan Guo, Gaoyu Song, Yi Huang, Lecheng Wang, Yani Zhang * and Tietao Wang*.Type II Toxin-Antitoxin Systems in Pseudomonas aeruginosa.Toxins, 2023, 15(2), 164; 

3.    Meng Li, Congcong Guan, Gaoyu Song , Xiaoxi Gao, Weina Yang, Tietao Wang, Yani Zhang. Characterization of a Conjugative Multidrug Resistance IncP-2 Megaplasmid, pPAG5, from a Clinical Pseudomonas aeruginosa Isolate. Microbiol Spectr,2022,10, e01992-01921.

4.      Yani Zhang, Meng Li, Congcong Guan, Yun Zhou, Juan Peng, Haihua Liang. Genomic characterization of clinical Pseudomonas aeruginosa isolate PAG5 with a multidrug-resistant megaplasmid from China. J Glob Antimicrob Resist. 2020(IF:2.899)

5.      Yani Zhang, Chao Zhang, Xiao Du, Yun Zhou, Weina Kong, Gee W Lau, Gukui Chen, Kohli Gurjeet Singh, Liang Yang, Tietao Wang, Haihua Liang.Glutathione Activates Type III Secretion System Through Vfr in Pseudomonas aeruginosa. Front Cell Infect Mi 2019, 9.

6.      Weina Kong, Mengmeng Dong, Rong Yan, Qingqing Liang, Huiqun Zhang, Wei Luo, Yani Zhang, Haihua Liang and Kangmin Duan. A unique ATPase, ArtR (PA4595), represses the type III secretion system in Pseudomonas aeruginosa. Front. Microbiol., 21 March 2019 | https://doi.org/10.3389/fmicb.2019.00560.

7.      Yufeng Du, Li Liu , Chunping Zhang, Yani Zhang. Two residues in Staphylococcus aureus alpha-hemolysin related to hemolysis and self-assembly. Infection and Drug Resistance. 2018, (11) 1271-1274(IF:3.779)

8.      Yisong Xu, Cheng Zhang, Hui Liang, Shanshuang Hu, Pengkun Li, Linna Liu, Xianglong Duan, Chao Chen, Yani Zhang* & Penggao Dai*. Dishevelled 1, a pivotal positive regulator of the Wnt signalling pathway, mediates 5-fluorouracil resistance in HepG2 cells. ARTIFICIAL CELLS, NANOMEDICINE, AND BIOTECHNOLOGY, 2018 ,(46:192-200(IF:5.6)

9.      Huiqin Liu, weina Kong, weina Yang, Gukui Chen, Haihua Liang, Yani Zhang*. Multilocus sequence typing and variations in the oprD gene of Pseudomonas aeruginosa isolated from a hospital in China. Infection and Drug Resistance.2018, (11) ,45—54(IF:3.779)

10.      Yani Zhang, Jing Qin, Boren Tan, Weina Kong, Gukui Chen, Chao Zhang and Haihua Liang. The P-Type ATPase PA1429 Regulates Quorum-Sensing Systems and Bacterial Virulence. Frontiers in microbiology , 2017, doi: 10.3389/fmicb.2017.02449(IF:4.019)

11.  Ying Wang, Yani Zhang, Yanli Guo, Xiaofeng Kang. Fast and precise detection of DNA methylation with tetramethylammonium-filled nanopore. Scientific Reports 2017.7(1):183

12.  Jing Duan, Sha Zhuo, Fujun Yao, Yani Zhang, Xiaofeng Kang. A Single-molecule Mycobacterium Smegmatis Porin A Protein Nanopore Sensor for   Host-Guest Chemistry.Chinese Journal of Analytical Chemisty.2016, (44)12,1801-1807

13.  Yani Zhang*, Xiaolong Shao, Shihong Wang, Siqi Zhang. Effect of Glutathione on Pyocyanin Production in Pseudomonas aeruginosa. Asian J. Chem., 2014, 26(11), 3265-3269

14.   Fujun Yao, Yani Zhang, Yongfeng Wei, Xiaofeng Kang. Rapid and sensitive detection of HBV DNA with nanopore sensor. Chem. Commun., 2014,50, 13853-13856

15.  Zhang yaniDuan kangminGlutathione exhibits antibacterial activity and increases tetracycline efficacy against Pseudomonas aeruginosa. Science in China Series C. 2009.52(6):501-505.

16.  Yani Zhang, Yang Wei. The impact of glutathione on the gene expression of exoY and exoS in Pseudomonas aeruginosa. Acta Microbiologica Sinica2009.49(5):603-608

17.  铜绿假单胞菌中型分泌系统调控机制及针对性治疗的研究进展. 张译兮,张亚妮马艳玲,罗威,肖雅,孔伟娜. 微生物学通报,2019, 46(2): 362373

18.  张亚妮  孔伟娜  梁海华. 多元化遗传学教学尝试. 生物学通报,2018,(53330-32                           

19.  卓丽霞,王莹,张春萍,段静,张亚妮. 溶血素的表达及其纳米孔的制备,中国生物工程杂志,2017371):53-57

20.  段静, 卓莎,姚付军,张亚妮,亢晓峰. 基于MspA 蛋白质纳米孔传感器的主客体化学研究, 分析化学,20164412),1801-1807

21.  张思琪,赵季平,马梦星,张亚妮*,植被与土壤生物群落的反馈调节关系. 基因组学与应用生物学,2015 年, 34(5) 1097-1102

22.  张亚妮*,王世红,孙琼,李煜. N-乙酰半胱氨酸对铜绿假单胞菌的耐药性及绿脓菌素产量的影响. 中国药理学通报. 2014, 304:591-592

23.  张亚妮,段康民.活性氧在细菌耐抗生素机制中的作用.中国药理学通报.2010.26(9):1129-1132

24.  张亚妮,马艳玲.人工合成抗菌肽D2A21 基因的克隆和表达.基因组学与应用生物学.2010.29(3):453-456

25.  卫阳,张亚妮,段康民.铜绿假单胞菌铁与群体感应系统的调节.西北大学学报(自然科学版).2010.40(5):828-832

26.  张亚妮,梁海华,段康民.谷胱甘肽与铜绿假单胞菌致病性关系的研究.微生物学通报.2009.36(9):1418-1422

27.  张亚妮,段康民.谷胱甘肽对铜绿假单胞菌的抑制及对四环素敏感性的影响.中国科学C.2009.39(5):429-433

28.  张亚妮,杨亮,段康民.铜绿假单胞菌gshB基因突变对MexXY-OprM主动外排泵表达的影响.第四军医大学学报.2008.29(23):2123-2126

29.   张亚妮,董兆麟.一株产紫杉醇真菌发酵条件的研究.西北大学学报(自然科学版)2002,32(3):31031210




Educational Experience

2005.9 2009.7

  • 西北大学
  • 分子微生物学
  • Doctoral Degree in Science
  • With Certificate of Graduation for Doctorate Study
  • 全日制教育

1998.9 2001.7

  • 西北大学
  • 植物生理
  • Master's Degree in Science
  • With Certificate of Graduation for Study as Master's Candidates
  • 全日制教育

1994.9 1998.7

  • 西北大学
  • 生物技术
  • Bachelor's Degree in Science
  • University graduated
  • 全日制教育

Work Experience

2015.3 2016.3
  • 美国
  • 伊利诺伊大学香槟分校
  • 访问学者
2011.3 2014.12
  • 西北大学
  • 化学与材料科学学院
  • 博士后

Social Affiliations

Research Focus