Linyu Jiao
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Regioselective deoxygenative chalcogenation of 7-azindole N-oxides promoted by I2/PEG-200
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Journal:Organic & Biomolecular Chemistry

Abstract:We developed a general and sustainable approach for the regioselective deoxygenative chalcogenation of 7-azindole N-oxides; the combination of an internal oxidant and a green solvent has been used successfully for the synthesis of mono- and dichalcogenyl 7-azaindoles which are of pharmaceutical interest. The regioselectivity is tunable by the variation of the reaction conditions. I2/PEG was established as an efficient and reusable catalytic system for C–H chalcogenation. This developed methodology has great potential for practical utility, with a broad substrate scope, green reaction conditions, and operational simplicity.

Indexed by:Journal paper

Discipline:Natural Science

First-Level Discipline:Chemistry

Document Type:J

Volume:17

Page Number:10073–10087

Translation or Not:no

Included Journals:SCI、SSCI

Personal information

Professor
Supervisor of Doctorate Candidates
Supervisor of Master's Candidates

Name (English):Linyu Jiao

Name (Pinyin):jiaolinyu

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School/Department:School of Chemical Engineering

Administrative Position:Professor

Education Level:With Certificate of Graduation for Doctorate Study

Business Address:Room 517, School of Chemical Engineering

Gender:Male

Contact Information:+86-(0)15029011564

Degree:Doctoral degree

Status:Employed

Alma Mater:Technical University of Berlin

Discipline:Other specialties in Chemical Engineering and Technology
Chemical Engineering

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Honors and Titles:

仲英青年学者  2020-01-03

国家建设高水平大学公派研究生奖学金  2011-05-10

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